Senior Engineer, Fluidics Integration

San Diego, CA (On-site)
Hardware – Fluidics /
Full-Time /
Join ONI and Explore the Boundaries of Scientific Discovery!

At ONI, we are driven by a profound mission: to propel scientific discovery and combat diseases by granting everyone the ability to visualize, comprehend, and share the intricate microscopic details of life. Our revolutionary Nanoimager stands at the forefront of advancing cellular studies on a molecular level, making substantial contributions to the evolution of scientific knowledge.

We are actively seeking an enthusiastic and devoted Senior Engineer, Fluidics Integration to join our pioneering team and help develop next-generation automated microscopy workflows. We believe in the power of relentless curiosity and the pursuit of excellence, and we invite you to join us in shaping the future of scientific exploration and healthcare breakthroughs.

This role will report to the Director of Hardware and is based in our San Diego office.

    • Own projects within technical roadmap, from conception to completion and transfer to manufacturing
    • Develop fluidics automation systems and interfacing consumables, including flow channels, subsystems, and components
    • Characterize fluidics systems, including metrology, flow profile, pressure, leakage and materials interaction
    • Create diagrams of fluidics circuits and prototypes of products to be examined, tested, and refined
    • Evaluate reagent exchange and kinetic interactions through modeling and experimentation
    • Prototype and integrate components with instrument control systems, including through programming device controllers for PoC/prototype testing
    • Design and execute integration studies for designed consumables alongside product development, demonstrating proof-of-concept, feasibility and full system integration
    • Design and execute V&V testing, as well as component and sub-system testing through each phase of development
    • Produce and present technical reports of experimental results for review
    • Support development of secondary assembly processes and manufacturing scale-up
    • Collaborate with chemists, biologists, and applications experts on the development of consumables that meet specific customer needs
    • Collaborate with software engineers on the design and automation of fluidics and complete workflows
    • Assist in the identification and selection of vendors for critical system components and materials
    • Establish critical parameters and tolerances for raw materials, custom components, and subassemblies to inform manufacturing and quality processes

Required Skills and Qualifications:

    • Bachelor’s degree with 5+ years or advanced degree with 3+ years of industry experience
    • Experience designing and integrating automation and control systems into fluidic systems and components/consumables/platforms
    • Working knowledge of Python
    • Experience using rapid prototyping tools (laser cutting, 3D printing, machining)
    • Experience using CAD software (SolidWorks or Inventor) is preferred
    • Theoretical and practical knowledge base in physics, especially, hydrodynamics, for micro- and macro-scale regime fluidic flow
    • Designed, prototyped, and scaled fluidics system architectures
    • Fluidic design, testing, and automation, using both hydraulic and pneumatic principles
    • Sensor integration, signal processing, and closed-loop control
    • Independently generate rigorous data sets and analyses and drive critical decisions and down-selections
    • Practical biological knowledge to support development of consumables that interface with cells and tissues for scientific analysis

At ONI, we understand that a fulfilling career involves more than just challenging work - it's about enjoying a well-rounded experience. When you become a part of our team, you not only contribute to groundbreaking research but also enjoy a range of benefits designed to enhance your life both inside and outside the workplace.

    • Competitive Compensation
    • Flexible Paid Time Off
    • Quarterly Wellbeing Days Off
    • 11 Company Holidays
    • Medical, Dental and Vision
    • Gym Access via ARE: State-of-the-art fitness and wellness facilities in Sorrento Valley, Torrey Pines, and UTC
    • 401k
$130,000 - $148,000 a year
As an equal opportunity employer, we prioritize fairness and respect, ensuring every team member thrives regardless of their background. We are committed to diversity and inclusion in the workplace. 

If you are driven by innovation, eager to make a significant impact in the realm of scientific and medical research, and possess the skills and passion we are looking for, we invite you to apply and be a part of our mission to improve our understanding of the details of life.