Staff Systems Engineer

San Diego, CA (On-site)
Hardware – Systems /
Full-Time /
Join ONI and Explore the Boundaries of Scientific Discovery!

At ONI, we are driven by a profound mission: to propel scientific discovery and combat diseases by granting everyone the ability to visualize, comprehend, and share the intricate microscopic details of life. Our revolutionary Nanoimager stands at the forefront of advancing cellular studies on a molecular level, making substantial contributions to the evolution of scientific knowledge.

We dedicate ourselves to broadening the realms of human potential, and we are actively seeking an enthusiastic and devoted Staff Systems Engineer to join our pioneering team located in San Diego. We believe in the power of relentless curiosity and the pursuit of excellence, and we invite you to join us in shaping the future of scientific exploration and healthcare breakthroughs.

As a Staff Systems Engineer at ONI, you will be responsible for systems-level design and development from concept to launch and manufacturing scale-up. This role involves producing new products and sustaining existing products used for super-resolution microscopy.

Your Role at ONI:

    • Lead a team of 3-4 engineers focused on development, system integration and testing of fluidics automation projects
    • Systems leadership in a portfolio of workflows that bring together microscopy, fluidics, data science, consumables, and biochemistry to enable scientific discoveries.
    • Contribute to system design and documentation to manage interdependencies in a highly sophisticated super-resolution microscopy system
    • Participate in the process of converting market requirements into product requirements into design specification
    • Contribute to a multidisciplinary team for the system and subsystem design and development, covering a variety of domains including optical, mechanical, fluidic, electrical, and software/firmware
    • Perform risk analysis, develop test plans, coordinate, and execute verification and validation testing of subsystems and systems
    • Improve and standardize processes and protocols for system verification to yield confidence in results and quality products
    • Ensure system documentation is complete and organized, and released/tracked with appropriate stakeholder sign-off
    • Create and maintain standards for engineering documentation, including definition and documentation of design work and interfaces between biochemistry, hardware systems & consumables, and software
    • Support the progression of products through the various phases of development and the transfer of new products into manufacturing
    • Work with Customer Support and Product Lifecycle Engineering to ensure customer experience and insights from released products are fed back into new product design
    • Mentor team members through design & development process, helping to reinforce best practices in a growing and maturing R&D organization
    • Support definition and proposals for future architectures and roadmap planning including evaluating new technologies, identifying opportunities to combine existing product functionalities, and generating novel IP

Essential skills and qualifications:

    • Systems engineering of sophisticated projects to develop multicomponent Life Sciences research tools, incl. optical and consumable components
    • Owned development of optical and/or consumable product functional requirements
    • Participated in design of verification and validation studies for novel hardware products
    • Experience with DOE with JMP or equivalent software packages
    • Understanding of materials used in fluidic consumables and appropriate applications for different products and systems
    • Interfaced with customer-facing teams to design and implement product improvements
    • Preparation of technical documentation e.g., block diagrams, standard operating procedures, product and quality requirements
    • Proactive identification of improvement opportunities related to functionality, robustness, scalability
    • Root cause analysis of manufacturing issues
    • Effective time management of own time and team
    • Minimum 3 years of industry experience as a Systems Engineer
    • Minimum 5 years of industry experience as an Engineer
    • Masters or PhD in relevant technical discipline e.g. Mechanical/Optical/Electrical Engineering
$145,000 - $160,000 a year

At ONI, we understand that a fulfilling career involves more than just challenging work - it's about enjoying a well-rounded experience. When you become a part of our team, you not only contribute to groundbreaking research but also enjoy a range of benefits designed to enhance your life both inside and outside the workplace. 

As an equal opportunity employer, we prioritize fairness and respect, ensuring every team member thrives regardless of their background. But that's not all - our perks include:

Competitive Compensation We recognize and reward your talent. Enjoy a competitive salary that reflects your expertise and contributions, ensuring your hard work is recognized.
Flex PTO plus 11 federal holidays and 4 dedicated wellbeing days.
Gym Access via ARE: Sorrento Valley, Torrey Pines, and UTC
401K via ADP
Life Insurance
Medical with Anthem Blue Cross
Dental with Anthem Dental
Perks at Work: Enjoy exclusive discounts and deals through our perks at work program, adding value to your everyday life.
VSP Vision: Your vision matters. Benefit from our eye care program with VSP Vision

If you are driven by innovation, eager to make a significant impact in the realm of scientific and medical research, and possess the skills and passion we are looking for, we invite you to apply and be a part of our mission to improve our understanding of the details of life.